by Cancer & Oncotherapy | Apr 14, 2022
Abstract: Background: Radical prostatectomy, a standard management approach for localized Prostate Cancer (PC), may cause a stress response associated with immune modulating effects. Regional anesthesia was hypothesized to reduce the immune effects of surgery by...
by Cancer & Oncotherapy | Apr 14, 2022
Abstract: Background: Colonic stenting has emerged as preferred palliative treatment for left sided malignant obstructions. It shortens hospital stays, decreases healthcare cost, reduces permanent stoma rates, and expedites the start of chemotherapy. The role of...
by Cancer & Oncotherapy | Apr 14, 2022
Abstract: This discussion covers changes in the provision of cancer genetic testing and screening in the United States since the passage of the 2010 Patient Protection and Affordable Care Act (ACA), with a focus on benefits for the marginalized. Similar reforms have...
by Cancer & Oncotherapy | Feb 16, 2022
Abstract: Acute lymphoblastic leukemia (ALL) and multiple myeloma (MM) are characterized by a monoclonal expansion of B- and/or T-cell lymphocyte progenitor/plasma cells, respectively. These diseases can be monitored by the detection of clonally rearranged...
by Cancer & Oncotherapy | Jan 25, 2022
Abstract: Lymphedema of upper limbs is a condition that usually arises after breast cancer treatment. The partial or total removal of axillary lymph nodes and the subsequent radiotherapy could lead to an incorrect discharge of lymph, which stagnates in the skin...
by Cancer & Oncotherapy | Jan 25, 2022
Abstract: Several alterations in the gastrointestinal tract which occur after appendectomy or cholecystectomy have been suggested to raise the risk of developing colorectal carcinoma. Given the frequency that these procedures are performed, we sought to determine...
by Cancer & Oncotherapy | Jan 25, 2022
Abstract: Pancreatic cancer is rarely diagnosed during pregnancy; it usually manifests with symptoms such as epigastric pain, vomiting, weight loss, and jaundice, rarely mimicking the hemolysis,elevated liver enzymes, and low platelet count syndrome. It has been...
by Cancer & Oncotherapy | Jan 25, 2022
Abstract: We present a case of unforeseen ureteral metastasis from a primary breast cancer. A ureteral injury leak was postoperatively recognized after a hysterectomy and bilateral oophorectomy were performed. Subsequent repair with a psoas hitch ureteral re-implant...
by Cancer & Oncotherapy | Jan 25, 2022
Abstract: Aim: The main goal of this investigation was to evaluate the influence of positive beta haemolytic streptococci culture from the genital tract on patients receiving radiation therapy who suffer from cervical cancer. The other aim was to observe radiation...
by Cancer & Oncotherapy | Jan 25, 2022
Abstract: The long-term treatment with tamoxifen can alter the lipid profile of patients with breast cancer. Only a few studies associated the plasma concentrations of tamoxifen, endoxifen, and 4-hydroxytamoxifen with blood lipids, which is relevant as the...
by Cancer & Oncotherapy | Jan 25, 2022
Abstract: Photodynamic therapy (PDT) is a highly promising, clinically approved, and non-invasive treatment modality for several cancer types. A typical PDT action requires, light, tissue oxygen, and a photosensitizer (PS), which are combined to generate cytotoxic...
by Cancer & Oncotherapy | Jan 19, 2022
Abstract: The lack of an effective treatment against cancer is not only due to its huge heterogeneity and complexity, but also to the fact that we do not entirely understand this disorder, highlighting the question of how cancer originates. Among the proposed models...
by Cancer & Oncotherapy | Jan 19, 2022
Abstract Background: Low-density neutrophils (LDN) have been shown to be increased in peripheral blood in patients with various diseases and closely related to immune-mediated pathology. However, the frequency and function of LDN in circulating blood of the patients...
by Cancer & Oncotherapy | Jan 18, 2022
Abstract Biliary tract cancers (BTCs) are a group of highly aggressive malignant tumors with a poor prognosis. The current diagnosis is based mainly on imaging and intraoperative exploration due to brush cytology havinga low sensitivity and the standard markers, such...
by Cancer & Oncotherapy | Aug 17, 2021
Abstract: In a review published in April 2021 in Cancer Letters (Rovigatti, U.: “The glycosphingolipid GD2 as an effective but enigmatic target of passive immunotherapy in children with aggressive neuroblastoma (HR-NBL) ”CL, 503: pp 220-230), I suggested that the...
by Cancer & Oncotherapy | Jun 7, 2021
Abstract: Circulating tumor cells (CTC) seed cancer metastases; however, the underlying cellular and molecular mechanisms remain unclear. CTC clusters were less frequently detected but more metastatic than single CTCs. Using intravital multiphoton microscopic imaging,...
by Cancer & Oncotherapy | Apr 26, 2021
Abstract: Prostate cancer is the most common cancer in males and a major cause of cancer-related morbidity and mortality in men. Current treatments of prostate cancer with androgen deprivation therapy are initially very effective. Beneficial responses, however, are...
by Cancer & Oncotherapy | Apr 26, 2021
Abstract: Cancer is one of the diseases with the highest incidence nowadays. In men, prostate cancer is the most frequent and its incidence increases with age. The used treatment is focused on blocking the effect of androgens, but this is not completely successful...
by Cancer & Oncotherapy | Apr 26, 2021
Abstract Cell migration is crucial for many physiological and pathological process. Following the lung injury, proliferation and migration of lung epithelial cells to the epithelial lining of alveoli and airways in the lung are pivotal for remodeling and repair of the...
by Cancer & Oncotherapy | Apr 26, 2021
Abstract Regional lymph node metastases in patients with carcinoma of the esophagus are an important prognostic factor. According to the eighth edition of the TNM classification of Malignant Tumors isolated tumor cells (ITCs) are defined as ”single tumor cells or...
by Cancer & Oncotherapy | Jul 12, 2020
Abstract: Lung cancer is the leading cause of cancer-death worldwide. In the United States, The U.S. Preventative Services Task Force (USPTSF) approved screening for current or former smokers aged 55- 80 based on the results of the National Lung Screening trial...
by Cancer & Oncotherapy | Jul 12, 2020
Abstract: Although the chemosensitizing effect of Dexamethasone (DEX) was previously reported, this study aimed to explore how far cotreatment of breast cancer cells with paclitaxel (PTX) and DEX mimics the anticancer effect of nanoformulated PTX. To establish this...
by Cancer & Oncotherapy | Jul 12, 2020
Abstract: Oxidant species including Reactive oxygen species (ROS) play a vital role in mediating diverse cellular signalling and apoptosis in normal cells. Excess oxidant species can oxidize numerous vital molecules to promote the development and progression of many...
by Cancer & Oncotherapy | Jul 12, 2020
Abstract: Introduction: Osteoid osteomas (OO) are small, well-defined, benign bone tumors of the young that are commonly found in long bones. In rare circumstances, when present elsewhere, they can mimic the symptoms of other pathologies pertaining to that area....
by Cancer & Oncotherapy | Jul 12, 2020
Abstract: Dermoid cysts are benign tumors rarely arising from the cecum. Also, including this report, 10 cases have been described in the literature, to our knowledge. Dermoid cysts are benign tumors rarely found in the cecum. A literature research has found only 9...
by Cancer & Oncotherapy | Jul 12, 2020
Abstract: In the last several decades, advancements in chemotherapy have improved the overall survival of cancer patients. These agents, however, are associated with adverse effects, including various kidney lesions. This review summarizes the nephrotoxic potential of...
by Cancer & Oncotherapy | Jul 12, 2020
Abstract: A low erythropoietin (EPO) level is a minor diagnostic criterion for polycythemia vera (PV). Controversies exist regarding the diagnostic value of a low EPO level when considering increasing availability of advanced molecular testing. We assessed the role of...
by Cancer & Oncotherapy | Jul 12, 2020
Abstract: Brown tumors of bone are highly vascular, lytic bone lesions representing a reparative cellular process rather than a neoplastic process seen in patients with hyperparathyroidism. These tumors may behave aggressively and can be destructive. We present a case...
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